Wound Care – Squirtable Elastic Surgical Glue

Wound Care – Squirtable Elastic Surgical Glue

Nurses who  work in  Wound Care  will be interested to hear about  MeTro the new Squirtable Elastic Surgical Glue   It is a highly elastic and adhesive surgical glue that quickly seals wounds without the need for common staples or sutures.

‘Biomedical engineers from the University of Sydney and the United States collaborated on the development of the potentially life-saving surgical glue. MeTro’s high elasticity makes it ideal for sealing wounds in body tissues that continually expand and relax  such as lungs, hearts and arteries- that are otherwise at risk of re-opening.

MeTro sets in just 60 seconds once treated with UV light, and the technology has a built-in degrading enzyme which can be modified to determine how long the sealant lasts — from hours to months, in order to allow adequate time for the wound to heal.

The liquid or gel-like material has quickly and successfully sealed incisions in the arteries and lungs of rodents and the lungs of pigs, without the need for sutures and staples.

Lead author of the study, Assistant Professor Nasim Annabi from the Department of Chemical Engineering at Northeastern University, oversaw the application of MeTro in a variety of clinical settings and conditions.

“The beauty of the MeTro formulation is that, as soon as it comes in contact with tissue surfaces, it solidifies into a gel-like phase without running away,” she said.

“We then further stabilise it by curing it on-site with a short light-mediated crosslinking treatment. This allows the sealant to be very accurately placed and to tightly bond and interlock with structures on the tissue surface.”

The University of Sydney’s Professor Anthony Weiss described the process as resembling that of silicone sealants used around bathroom and kitchen tiles.

“When you watch MeTro, you can see it act like a liquid, filling the gaps and conforming to the shape of the wound,” he said.

“It responds well biologically, and interfaces closely with human tissue to promote healing. The gel is easily stored and can be squirted directly onto a wound or cavity.

“The potential applications are powerful — from treating serious internal wounds at emergency sites such as following car accidents and in war zones, as well as improving hospital surgeries.”

Professor Khademhosseini from Harvard Medical School was optimistic about the study’s findings.

“MeTro seems to remain stable over the period that wounds need to heal in demanding mechanical conditions and later it degrades without any signs of toxicity; it checks off all the boxes of a highly versatile and efficient surgical sealant with potential also beyond pulmonary and vascular suture and staple-less applications,” he said.

The next stage for the technology is clinical testing, Professor Weiss said.

“We have shown MeTro works in a range of different settings and solves problems other available sealants can’t. We’re now ready to transfer our research into testing on people. I hope MeTro will soon be used in the clinic, saving human lives.”

The Nurses for Nurses Network provides great information and CPD  on an array of nursing topics including wound care in a range of easy learning ways including webinars and quizzes on the latest information that Nurses need to know – remember the Nurses for Nurses Network was created by Australian Nurses for Nurses!  www.nursesfornurses.com.au

Source University of Sydney. “‘Squirtable’ elastic surgical glue seals wounds in 60 seconds: Emergency treatments could be transformed, saving lives.” ScienceDaily. ScienceDaily, 5 October 2017. <www.sciencedaily.com/releases/2017/10/171005102741.htm>.

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